Tips And Advice for Living in a Fifth Wheel Trailer. Living in a fifth wheel trailer is a lot different from taking shorter, temporary trips. Packing, deciding on which items are necessities, and figuring out what to leave behind isn't an easy task. If the fifth wheel trailer will become the sole home, there are a lot of decisions to be made about what to do with the items that won't fit. A little planning before hitting the road will ease the transition and help travelers make the best decisions.